How is chronic fatigue diagnosed?

Diagnosing chronic fatigue can be tricky because there’s no single test for it. Doctors typically use a process of elimination to rule out other conditions such as thyroid disease, anemia, sleep apnea, and depression. A thorough health history, physical exam, and sometimes blood tests are involved. For a diagnosis of chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME), symptoms must last for at least six months and include post-exertional malaise (worsening of symptoms after even minor physical or mental activity).

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